Cover of: Diseases of the human carotid body | Donald Heath

Diseases of the human carotid body

  • 205 Pages
  • 1.35 MB
  • English
Springer-Verlag , London, New York
Carotid body -- Pathophysiology, Carotid body -- Histopathology, Carotid Body -- path
StatementDonald Heath, Paul Smith.
ContributionsSmith, Paul, 1944-
LC ClassificationsRC409 .H43 1991
The Physical Object
Paginationxii, 205 p. :
ID Numbers
Open LibraryOL2028684M
ISBN 100387196870, 3540196870
LC Control Number91004837

This book is an attempt to redress this unsatisfactory situation. During the last few years our understanding of the detailed histology and ultrastructure of the human carotid body.

Diseases of the human carotid body. Diseases of the human carotid body book [Donald Heath; Paul Smith] Home. WorldCat Home About WorldCat Help. Search. Search for Library Items Search for Lists Search for Contacts Search for a Library. Create Book\/a>, schema:CreativeWork\/a> ; \u00A0\u00A0\u00A0 library.

Read "Diseases of the Human Carotid Body" by Paul Smith available from Rakuten Kobo. Ever since its discovery in the carotid body has remained an organ of mystery. Originally described as a ganglion, Brand: Springer London.

Diseases of the Human Carotid Body. Authors: Heath, Donald, Smith, Paul Free Preview. Buy this book eB68 This book is an attempt to redress this unsatisfactory situation. During the last few years our understanding of the detailed histology and ultrastructure of the human carotid body.

Diseases of the Human Carotid Body Article (PDF Available) in Journal of Clinical Pathology 46(6) June with 46 Reads How we measure 'reads'.

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Buy Diseases of the Human Carotid Body by Donald Heath, Paul Smith from Waterstones today. Click and Collect from your local Waterstones or get FREE UK delivery on orders over £ The human carotid body in health and disease. Professor Donald Heath.

Corresponding Author. Department of Pathology, University of Liverpool, Liverpool, U.K. Department of Pathology, Duncan Building, Royal Liverpool Hospital, Liverpool L69 3BX, for more papers by this author.

The carotid body (CB) is an arterial chemoreceptor organ located in the carotid bifurcation and has a well-recognized role in cardiorespiratory regulation. The CB contains neurosecretory sensory cells (glomus cells), which release transmitters in response to hypoxia, hypercapnia, and acidemia to activate afferent sensory fibers terminating in the respiratory and autonomic brainstem centers.

Diseases of the Human Body 6th Edition by Carol D. Tamparo PhD CMA-A (AAMA) (Author) out of 5 stars 61 ratings. ISBN ISBN Why is ISBN important. ISBN. This bar-code number lets you verify that you're getting exactly the right version or edition of a book.

The digit and digit formats both s: Get this from a library. Diseases of the Human Carotid Body. [Donald Heath; Paul Smith] -- This highly original volume with its unique comprehensive coverage of diseases of the human carotid body results from the authors' 20 years research into the subject and is destined to become a.

Abstract. The carotid body does not maintain a uniform histological appearance throughout adult life but shows changes related to ageing.

In general terms there is a progressive loss of glomic substance and alteration of the structure, with a change in the proportion of its cytological components. Full text Full text is available as a scanned copy of the original print version.

Get a printable copy (PDF file) of the complete article (K), or click on a page image below to browse page by : Anne M Mcnicol. Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full : Anne M Mcnicol. The carotid body functions as a sensor: it responds to a stimulus, primarily O 2 partial pressure, which is detected by the type I (glomus) cells, and triggers an action potential through the afferent fibers of the glossopharyngeal nerve, which relays the information to the central nervous system.

Stimulus. The carotid body peripheral chemoreceptors are primarily sensitive to decreases in the. Treatment for carotid body tumors is generally very safe with good outcomes. However, all surgery involves risks. One possible complication is stroke, but this is rare and happens in less than 2% of carotid body tumor removals.

The risk is highest for patients who have large tumors and need to have vascular repair or replacement. PhD Project - Genetic exploration of the carotid body: Unravelling mechanisms of neurogenic hypertension at University of Auckland, listed on Carotid bodies (CBs) are peripheral chemoreceptors that sense changes in blood O2, CO2, and pH levels.

Apart from ventilatory control, these organs are deeply involved in the homeostatic regulation of carbohydrates and lipid metabolism and inflammation. It has been described that CB dysfunction is involved in the genesis of metabolic diseases and that CB overactivation is present in animal.

Introduction. The carotid body (CB) is the primary chemosensory organ in humans. It responds to hypoxaemia, increased arterial carbon dioxide, changes in pH, hypoglycaemia, and changes in blood flow.

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1 CBs are located at the inferomedial aspect of the common carotid artery bifurcation in the peri-adventitial tissue.

1 They are highly innervated and have the highest per-gram perfusion of any. Carotid body as a sensor of low glucose. The first evidence linking the CB with glucose metabolism was reported by Alvarez-Buylla and de Alvarez-Buylla (), Alvarez-Buylla and Roces de Alvarez-Buylla ().More recently, in vivo studies demonstrated that the counter-regulatory response to insulin-induced hypoglycemia is impaired in CB-resected dogs (Koyama et al., ).

Learn about carotid artery disease symptoms, prevention and treatment options including stenting, angioplasty and carotid endarterectomy. Venous malformation, Peripheral artery disease, Carotid body tumor, Median arcuate ligament syndrome, Varicose vein, Carotid insufficiency, Mesenteric ischemia, Aortic aneurysm, Nutcracker syndrome.

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lists trials that are related to Carotid body tumor. Click on the link to go to to read descriptions of these studies.

Please note: Studies listed on the website are listed for informational purposes only; being listed does not reflect an endorsement by GARD or the strongly recommend that you talk with a trusted healthcare.

Heath D, Jago R, Smith P. The vasculature of the carotid body. Cardiovasc Res. Jan; 17 (1)– Grimley PM, Glenner GG. Ultrastructure of the human carotid body.

A perspective on the mode of chemoreception. Circulation. Apr; 37 (4)– Pearse AG. The carotid body (CB; also known as the glomus caroticum, carotid corpuscle, carotid ganglion, and carotid gland) is a neural crest-derived paired ovoid mass of tissue, around 2 mm in diameter in humans and less than 1 mm in rats.

Its small size explains why it was referred to as ganglion minimum in. Carotid Artery Disease From Bench to Bedside and Beyond.

This book will bring out the state of art of carotid stenosis in the basic and clinical approaches for better understanding of the mechanisms and useful therapies for these disease.

The aortic and carotid body forms a part of the respiratory system in humans. The carotid body is located on carotid artery and aortic body is located on aortic arch. Carotid arteries are situated on the neck and aortic arch is present in the heart.

Aortic arch supplies blood to arms, neck, and head. Unilateral carotid body denervation has been proposed as treatment for sympathetic-related human diseases such as systolic heart failure, hypertension, obstructive sleep apnea, and cardiometabolic diseases.

The long-term therapeutic effects of carotid body removal will be maintained if the remnant ". Bhattacharya, S. Chaturvedi, in Primer on Cerebrovascular Diseases (Second Edition), Abstract.

Carotid artery atherosclerotic disease is a well-established risk factor for ischemic stroke. While often asymptomatic, the disease could present with symptoms resulting from low hemodynamic pressure in the carotid system or from emboli arising from carotid plaque.

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J Physiol Physiology of human carotid body cells receptors and enzymes) thought to be relevant to the physiology of the CB or its response to drugs, has been described in two recent papers (Fagerlund et al. ; Mkrtchianetal).Nonetheless,theactualfunctional properties of human CB cells remain as yet unstudied.

If the address matches an existing account you will receive an email with instructions to reset your password. Carotid body resection in chronic obstructive pulmonary disease.

Chest. ; Crossref Medline Google Scholar; Stulbarg MS, Winn WR, Kellett LE. Bilateral carotid body resection for the relief of dyspnea in severe chronic obstructive pulmonary disease. Physiologic and clinical observations in three patients.

Chest. ;   The carotid body (CB) is a polymodal chemoreceptor located in the carotid bifurcation, which is activated by hypoxemia, hypercapnia, acidosis, reduction of arterial blood flow, temperature change and low levels of glucose [1–4].Reflex cardiorespiratory responses are characterized by hyperventilation and increased sympathetic discharge to the vascular beds and the heart.The carotid body (CB) is a neural crest-derived organ whose major function is to sense changes in arterial oxygen tension to elicit hyperventilation in hypoxia.

The CB is composed of clusters of neuron-like glomus, or type-I, cells enveloped by glia-like sustentacular, or type-II, cells. Responsiveness of CB to acute hypoxia relies on the inhibition of O2-sensitive K+ channels in glomus cells.